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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42BPG
All Species:
8.79
Human Site:
S583
Identified Species:
19.33
UniProt:
Q6DT37
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DT37
NP_059995.2
1551
172459
S583
E
Q
R
L
E
E
S
S
Q
A
K
T
I
H
T
Chimpanzee
Pan troglodytes
XP_001146567
1517
167558
E578
R
A
G
L
Q
A
Q
E
Q
E
L
C
R
A
Q
Rhesus Macaque
Macaca mulatta
XP_001118237
1589
175947
S583
E
Q
R
L
E
E
S
S
Q
A
K
T
I
H
T
Dog
Lupus familis
XP_540878
1547
171825
S578
E
R
S
L
E
K
E
S
F
R
V
K
T
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80UW5
1551
172128
K584
K
Q
E
S
S
Q
A
K
T
V
H
A
A
P
E
Rat
Rattus norvegicus
O54874
1732
197045
S652
D
R
K
L
R
E
Q
S
R
H
Y
S
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513203
1718
195063
L663
S
K
Q
L
E
N
E
L
E
G
L
K
Q
K
Q
Chicken
Gallus gallus
XP_001231343
1637
185418
K576
E
R
S
E
Q
Y
S
K
Q
L
E
S
E
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696317
1166
130245
E296
T
K
M
T
E
E
L
E
G
L
K
N
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
R652
K
L
S
H
Q
Q
T
R
H
N
M
E
L
E
A
Honey Bee
Apis mellifera
XP_395596
1741
197744
N669
E
K
L
E
V
Q
Y
N
E
N
L
N
Q
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
94.5
87.3
N.A.
85
44.9
N.A.
45.8
46.3
N.A.
37.1
N.A.
37.4
37.3
N.A.
N.A.
Protein Similarity:
100
90.8
95.7
91.6
N.A.
89.6
62.1
N.A.
62.6
63.8
N.A.
52.2
N.A.
56
54.3
N.A.
N.A.
P-Site Identity:
100
13.3
100
26.6
N.A.
6.6
20
N.A.
13.3
20
N.A.
20
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
20
100
40
N.A.
26.6
53.3
N.A.
33.3
46.6
N.A.
26.6
N.A.
33.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
0
0
19
0
10
19
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
46
0
10
19
46
37
19
19
19
10
10
10
10
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
10
10
10
0
0
19
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
19
10
0
% I
% Lys:
19
28
10
0
0
10
0
19
0
0
28
19
10
10
0
% K
% Leu:
0
10
10
55
0
0
10
10
0
19
28
0
10
0
19
% L
% Met:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
19
0
19
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
28
10
0
28
28
19
0
37
0
0
0
19
19
28
% Q
% Arg:
10
28
19
0
10
0
0
10
10
10
0
0
10
0
0
% R
% Ser:
10
0
28
10
10
0
28
37
0
0
0
19
0
10
0
% S
% Thr:
10
0
0
10
0
0
10
0
10
0
0
19
10
0
19
% T
% Val:
0
0
0
0
10
0
0
0
0
10
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _